diff --git a/mindspore/_extends/builtin_operations.py b/mindspore/_extends/builtin_operations.py
index 6bd382c1b6..04dd443bde 100644
--- a/mindspore/_extends/builtin_operations.py
+++ b/mindspore/_extends/builtin_operations.py
@@ -14,6 +14,7 @@
 # ============================================================================
 """builtin_operations"""
 import numpy as np
+from mindspore.ops import functional as F
 from mindspore.common.tensor import Tensor
 from mindspore.common.dtype import dtype_to_nptype, get_py_obj_dtype
 
@@ -171,3 +172,13 @@ def tuple_to_array(x):
 def stop_gradient(x):
     """Implement `stop_gradient`."""
     return x
+
+
+def mixed_precision_cast(dst_type, x):
+    """Implement `mixed_precision_cast`."""
+    if isinstance(x, tuple):
+        res = list()
+        for item in x:
+            res.append(F.cast(item, dst_type))
+        return tuple(res)
+    return F.cast(x, dst_type)
diff --git a/mindspore/ccsrc/pipeline/pynative/base.h b/mindspore/ccsrc/pipeline/pynative/base.h
index 2a380d6900..eed522e7df 100644
--- a/mindspore/ccsrc/pipeline/pynative/base.h
+++ b/mindspore/ccsrc/pipeline/pynative/base.h
@@ -59,7 +59,7 @@ struct OpExecInfo {
 using OpExecInfoPtr = std::shared_ptr<OpExecInfo>;
 OpExecInfoPtr GenerateOpExecInfo(const py::args &args, py::list *const out_args);
 
-const std::set<std::string> ignore_infer_prim = {"make_ref"};
+const std::set<std::string> ignore_infer_prim = {"make_ref", "mixed_precision_cast"};
 }  // namespace pynative
 }  // namespace mindspore
 
diff --git a/mindspore/ccsrc/pipeline/pynative/pynative_execute.cc b/mindspore/ccsrc/pipeline/pynative/pynative_execute.cc
index a39a931b29..98b9e5b62d 100644
--- a/mindspore/ccsrc/pipeline/pynative/pynative_execute.cc
+++ b/mindspore/ccsrc/pipeline/pynative/pynative_execute.cc
@@ -57,7 +57,7 @@ using mindspore::tensor::TensorPy;
 
 const char SINGLE_OP_GRAPH[] = "single_op_graph";
 // primitive unable to infer value for constant input in PyNative mode
-const std::set<std::string> vm_operators = {"make_ref", "HookBackward", "stop_gradient"};
+const std::set<std::string> vm_operators = {"make_ref", "HookBackward", "stop_gradient", "mixed_precision_cast"};
 
 namespace mindspore {
 namespace pynative {
@@ -766,6 +766,9 @@ PynativeExecutor::PynativeExecutor() { grad_flag_ = false; }
 void PynativeExecutor::NewGraphInner(const py::object &cell, const py::args &args) {
   auto cell_id = GetId(cell);
   if (cell_graph_map_.count(cell_id) != 0) {
+    if (cell_resource_map_.find(cell_id) != cell_resource_map_.end()) {
+      resource_ = cell_resource_map_[cell_id];
+    }
     MS_LOG(DEBUG) << "Newgraph already compiled";
     return;
   }
@@ -774,6 +777,8 @@ void PynativeExecutor::NewGraphInner(const py::object &cell, const py::args &arg
 
   if (top_g_ == nullptr) {
     top_g_ = curr_g_ = g;
+    resource_ = std::make_shared<pipeline::Resource>();
+    cell_resource_map_[cell_id] = resource_;
     df_builder_ = std::make_shared<FuncGraph>();
     MS_LOG(DEBUG) << "First new graph" << top_g_.get();
     Pushp();
@@ -1075,6 +1080,7 @@ void PynativeExecutor::Clear(const std::string &flag) {
     MS_LOG(INFO) << "Clear res";
     (void)graph_map_.erase(flag);
     (void)cell_graph_map_.erase(flag);
+    (void)cell_resource_map_.erase(flag);
     Clean();
     // Maybe exit in the pynative runing op, so need reset pynative flag.
     auto ms_context = MsContext::GetInstance();
@@ -1086,6 +1092,7 @@ void PynativeExecutor::Clear(const std::string &flag) {
 
   MS_LOG(INFO) << "Clear";
   top_g_ = nullptr;
+  df_builder_ = nullptr;
   curr_g_ = nullptr;
   graph_info_map_.clear();
   std::stack<FuncGraphPtr>().swap(graph_p_);
@@ -1095,7 +1102,6 @@ void PynativeExecutor::Clean() {
   MS_LOG(INFO) << "Clean all res";
   Clear();
   grad_flag_ = false;
-  df_builder_ = nullptr;
   ad::CleanRes();
   pipeline::ReclaimOptimizer();
 }
diff --git a/mindspore/ccsrc/pipeline/pynative/pynative_execute.h b/mindspore/ccsrc/pipeline/pynative/pynative_execute.h
index 4a2c525534..850dc56691 100644
--- a/mindspore/ccsrc/pipeline/pynative/pynative_execute.h
+++ b/mindspore/ccsrc/pipeline/pynative/pynative_execute.h
@@ -115,6 +115,7 @@ class PynativeExecutor : public std::enable_shared_from_this<PynativeExecutor> {
   bool grad_flag_;
   std::unordered_map<std::string, FuncGraphPtr> graph_map_;
   std::unordered_map<std::string, FuncGraphPtr> cell_graph_map_;
+  std::unordered_map<std::string, ResourcePtr> cell_resource_map_;
   std::unordered_map<FuncGraphPtr, GraphInfo> graph_info_map_;
   std::stack<FuncGraphPtr> graph_p_;
   FuncGraphPtr top_g_;
diff --git a/mindspore/nn/wrap/loss_scale.py b/mindspore/nn/wrap/loss_scale.py
index 31dfb9f9ed..9cda88b26b 100644
--- a/mindspore/nn/wrap/loss_scale.py
+++ b/mindspore/nn/wrap/loss_scale.py
@@ -206,6 +206,7 @@ class TrainOneStepWithLossScaleCell(Cell):
     def __init__(self, network, optimizer, scale_update_cell=None):
         super(TrainOneStepWithLossScaleCell, self).__init__(auto_prefix=False)
         self.network = network
+        self.network.set_grad()
         self.network.add_flags(defer_inline=True)
         self.weights = optimizer.parameters
         self.optimizer = optimizer
diff --git a/tests/ut/python/ops/test_control_ops.py b/tests/ut/python/ops/test_control_ops.py
index 53b42b8f66..24c593c48c 100644
--- a/tests/ut/python/ops/test_control_ops.py
+++ b/tests/ut/python/ops/test_control_ops.py
@@ -20,6 +20,7 @@ import mindspore as ms
 from mindspore import Tensor
 from mindspore import context
 from mindspore import nn
+from mindspore.common import dtype as mstype
 from mindspore.ops import composite as C
 from mindspore.ops import functional as F
 from mindspore.ops import operations as P
@@ -639,3 +640,9 @@ def test_large_for_loop_with_continue_break():
     t = Tensor(np.ones([2, 3], dtype=np.float32))
     net = Net()
     net(t)
+
+
+def test_mixed_precision_cast():
+    x = Tensor(np.ones([2, 3], dtype=np.float32))
+    z = F.mixed_precision_cast(mstype.float16, x)
+    assert z.dtype == mstype.float16